MEF2D antibody

Catalog No. ABIN7254574

This anti-MEF2D antibody is a Rabbit Polyclonal antibody detecting MEF2D in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for MEF2D antibody (ABIN7254574)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2D antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MEF2D Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human MEF2D

Isotype: IgG

Application Details

Application Notes: IHC 1:35-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D

Background: This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. MEF2D (Myocyte Enhancer Factor 2D) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Development Angiotensin activation of ERK. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MEF2A.

UniProt: Q14814